Brown had four receptions (eight targets) for 50 yards and threw a 16-yard touchdown pass in Saturday's 22-19 playoff loss to Houston.
Brown is inactive for Sunday's game against the Jets.
Although he was referring to quarterback Josh Allen, Bills coach Sean McDermott implied that Brown and other starters could be rested in the finale against the Jets, The Buffalo News reports.
Brown hauled in only one of his four targets for 53 yards and a touchdown in the team's Week 16 loss to the Patriots. He also added one rush for three yards.
Brown caught three of eight targets for 26 yards during Sunday's 24-17 loss to the Ravens.
Brown caught three of four targets for 26 yards and completed his only pass attempt for a 28-yard touchdown to Devin Singletary in Thursday's 26-15 win over the Cowboys.
Brown caught two of four targets for 39 yards and a touchdown during Sunday's 20-3 win over Denver.
Brown caught nine of 14 passes for 137 yards and two touchdowns during Sunday's 37-20 win over Miami.
Brown caught five of 11 targets for 77 yards during Sunday's 19-16 loss to the Browns.
Brown corralled four of seven targets for 76 receiving yards during Sunday's 24-9 win against the Redskins.